1 Phytotherapy in the Management of Diabetes : 2 A Review 3

نویسندگان

  • Paolo Governa
  • Giulia Baini
  • Vittoria Borgonetti
  • Daniela Giachetti
  • Anna Rosa Magnano
  • Elisabetta Miraldi
  • Marco Biagi
چکیده

Phytotherapy has long been a source of medicinal products and many attempts to use 12 herbal medicine for the treatment of diabetes has been done over the years. Several medicinal 13 plants and their preparations demonstrated to act in key points of glucidic metabolism. The most 14 common mechanisms of action found include the inhibition of α-glucosidase and of AGE 15 formation, the increase of GLUT-4 and PPARs expression and the antioxidant activity. 16 Despite the large amount of literature available, the actual clinical effectiveness of medicinal plants 17 in controlling diabetes related symptoms is still controversial and there is a crucial need for 18 stronger evidence-based data. 19 In this review, an overview of the medicinal plants, which use in the management of diabetes is 20 supported by authoritative monograph, is provided. References to some species which are 21 currently under growing clinical investigation are also reported. 22

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تاریخ انتشار 2017